IN VIVO GENE EDITING OF MUSCLE STEM CELLS WITH ADENO-ASSOCIATED VIRAL VECTORS IN A MOUSE MODEL OF DUCHENNE MUSCULAR DYSTROPHY

In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy

Delivery of therapeutic transgenes with adeno-associated viral (AAV) vectors for treatment of myopathies has yielded encouraging results in animal models and early clinical studies.Although certain AAV serotypes efficiently target muscle fibers, transduction of the muscle stem cells, also known as satellite cells, is less studied.Here, we used a Pa

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Equivalent hazard magnitude scale

Hazard magnitude scales are widely adopted to Counter-Top Product facilitate communication regarding hazard events and the corresponding decision making for emergency management.A hazard magnitude scale measures the strength of a hazard event considering the natural forcing phenomena and the severity of the event with respect to average entities at

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The Effect of Internal and External Focus of Attention on Acquisition, Retention and Transfer of Dart Throwing in Mentally Retarded Children

The aim of this study was to investigate the effect of focus of attention on learning dart throwing in mentally retarded children.In this quasi-experimental study, 22 mentally retarded boys (age 10-12 years old) were randomly selected according to IQ (50-70) and were assigned to two homogenous attention (internal, external) groups after the pretest

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